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28 November, 2019 - 13:27 By Kate Sweeney

Fluidic Analytics unveils innovation at Lisbon summit

Fluidic Analytics in Cambridge, a specialist in protein analysis and the company behind in-solution diffusional sizing, launched a breakthrough innovation at PEGS Europe Protein and Antibody Engineering Summit in Lisbon.

The Cambridge University spin-out, which raised €27 million last year, believes that the new Fluidity One-W is set to revolutionise protein interaction analysis with the ability to accurately assess on-target protein interactions in solution, even in complex backgrounds.

Advancing the field of comprehensive protein analysis, the cutting-edge device can analyse protein interactions in crude biological backgrounds, such as cell lysates or blood plasm, using what the company calls “a brilliantly simple set-up that saves valuable research time.”

The Fluidity One-W can be used to confidently collect accurate and reliable protein interaction data thanks to the company’s proprietary microfluidic diffusional sizing technology. It can deliver both binding affinities and highly sought-after stoichiometry information from a single experiment, while also providing vital information about how the size of the protein changes during binding.

CEO Andrew Lynn said this “unique combination of information” can help scientists determine how strongly proteins are binding, how many protein molecules are binding at a time and whether the protein is binding to its target or to something unexpected.

The need for better ways to understand protein interactions was highlighted in a recent study in the journal Science Translational Medicine, which showed that 10 anti-cancer drugs currently in clinical trials do not interact with their targets in the way that clinicians thought they did.  

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