Brain gain for Nuclera as academia rushes for protein optimisation tech

03 May, 2024
Tony Quested
Highly respected academic institutions in Cambridge, wider UK and Belgium have installed protein expression optimisation technology from Cambridge biotech Nuclera.
Dr Michael Chen. Courtesy – Nuclera.

The company is rapidly accelerating protein expression and purification workflows through its benchtop protein system – eProtein Discovery™.

Endorsements through commercial uptake are growing apace. Nuclera reveals that it has has successfully completed 11 installs of its system, including at leading academic institutes.

Following the first launch installation at the University of Southampton, the technology has now been deployed in academic institutions including University College London, the Universities of Cambridge and Manchester, The Flanders Institute for Biotechnology (VIB) in Belgium and the CRUK Cambridge Institute.

Installations of the eProtein Discovery system across multiple academic laboratories in the UK and Europe, follows the company’s successful $58 million Series B financing round.

With additional installations scheduled throughout 2024, the commercial launch represents a significant milestone in providing access to the benchtop automated system.

Custom protein reagents, required in drug discovery, are challenging to manufacture both in terms of cost and time associated. The eProtein Discovery platform overcomes this unmet need by providing rapid access to challenging proteins in a benchtop system in less than 48 hours.

Accelerating drug discovery processes by up to 30x, the platform provides sequences and optimal conditions to inform protein manufacturing.

Dr Michael Chen, CEO and co-founder, Nuclera, said: “The commercial launch of our eProtein Discovery platform and placement in leading academic institutes marks a key milestone as we bring to the market a streamlined benchtop solution to accelerate protein production workflows and ultimately the drug discovery process.

“By launching the eProtein Discovery and reaching 11 installations to date, we are excited to see our technology aid drug development, enabling new drugs to reach the market faster to help patients with much-needed treatment.”